Identifying and Characterizing Preclinical MS

Recruiting now

Conditions studied: Multiple Sclerosis

In brief

The purpose of this research study is to try and identify risk factors and biologic changes that suggest that someone may go on to develop multiple sclerosis before a person has shown any symptoms of the disease.

Key facts

Study ID

NCT05787795

Run by

Yale University

People needed

1000

Starts

2022-06-21

Expected to finish

2033-06-30

Last updated by the study team

2025-11-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 18+
• Having one or more risk factors for multiple sclerosis, including one or more of the below:
• Individuals known to have a radiologically isolated syndrome
• Individuals with a family history of multiple sclerosis (first degree family member)
• Individuals with personal risk factors, which are known to include smoking, obesity, Epstein Barr virus infections, Vitamin D deficiency, genetic risk score

You may not qualify if…

• Currently pregnant
• Diagnosis of multiple sclerosis or any ongoing, systemic autoimmune disease
• Ongoing treatment with immunosuppressive medications

Where it is running

• Yale University — North Haven, Connecticut, United States (enrolling)

Full record on ClinicalTrials.gov

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