Endothelial Dysfunction and Non-cardiac Surgery

Recruiting now

Conditions studied: Surgery, Cardiac Death, Stroke, Myocardial Injury

In brief

Endothelial dysfunction is a cardiovascular disease hallmark. After non-cardiac surgery, cardiovascular events correlate with surgical outcomes. Understanding the role of endothelial function in these events is crucial. This research aims to study endothelial function and its association with cardiovascular events.

Key facts

Study ID

NCT05778981

Run by

University of Chile

People needed

200

Starts

2023-03-25

Expected to finish

2025-12-01

Last updated by the study team

2024-12-10

Who can join

Age: 45 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Signed informed consent
• Patients 45 years or older

You may not qualify if…

• Refuse to participate in the study
• Myocardial injury or acute myocardial infarction less than two weeks ago
• Patients who expect less than 2 days of hospitalization
• Patients in whom the troponin elevation is attributed to a secondary cause (for example, sepsis, pulmonary thromboembolism, electrical cardioversion, etc.)
• Use of chemotherapy less than 2 weeks ago

Where it is running

• Hospital Clínico de la Universidad de Chile — Independencia, Santiago Metropolitan, Chile (enrolling)

Full record on ClinicalTrials.gov

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