Exercise to Slow Cardiovascular Ageing Progression
Recruiting now
Conditions studied: Cardiac Ageing, Exercise, Cardiovascular
In brief
In ageing, deleterious alterations in cardiovascular (CV) structure and function increase risks of ageing-related cardiovascular disease (CVD). Investigators found that these CV alterations were associated with circulating serum metabolites, suggesting a metabolic basis to CV ageing. Investigators hypothesize that modification of these metabolites by intervention, such as exercise, may retard CV alterations and reduce CVD in ageing.
Key facts
- Study ID
- NCT05775484
- Run by
- National Heart Centre Singapore
- People needed
- 450
- Starts
- 2023-05-01
- Expected to finish
- 2050-12-31
- Last updated by the study team
- 2025-06-05
Who can join
Age: 21 and older, up to 100. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age >=21 years old
- Outdoor ambulant
You may not qualify if…
- Wheelchair or bed-bound
- Dementia
- Residing in sheltered or nursing home
- Cancer
- Participation in ongoing clinical trials that involve interventional drugs or devices
- Aneurysms
- Acute infections (in the last six months)
- Uncontrolled thyrotoxicosis
- Neuromuscular, musculoskeletal or rheumatoid disorders that are exacerbated by exercise
- Uncontrolled asthma or chronic lung disease
- Restrictive lung disease
Where it is running
- National Heart Centre Singapore — Singapore, Singapore, Singapore (enrolling)
Full record on ClinicalTrials.gov
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