Effects of Breathing and Attention Training (BAT) on Pain Modulation

Recruiting now · Not applicable

Conditions studied: Fibromyalgia

In brief

The hypersensitivity of fibromyalgia is associated with abnormal pain modulation within the CNS, but not with peripheral or central sensitization. Many brain areas that contribute to modulation of pain are known, but their testing is complex and expensive. Quantitative sensory testing is easier to perform and repeatable. Therefore, it will be used to evaluate the effects of Breathing Attention Training (BAT) on the hypersensitivity of FM participants. BAT is a form of mindfulness meditation shown to decrease FM symptoms and possibly pain sensitivity. We hypothesize that pain modulation of chronic pain patients is improved by BAT.

Key facts

Study ID

NCT05773482

Run by

University of Florida

People needed

40

Starts

2023-04-03

Expected to finish

2028-03-09

Last updated by the study team

2026-07-06

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Individuals diagnosed with fibromyalgia will have pain of duration > 6 months and meeting the 1990 Research Diagnostic Criteria for FM (ACR)
• Healthy, pain-free age matched controls without chronic pain

You may not qualify if…

• Personal or family history of photosensitive epilepsy
• Prior history of cancer or diabetes
• Patients must be willing to discontinue their analgesics, hypnotics, anxiolytics, or anti-depressants during the study period for at least 5 half-lives.

Where it is running

• University of Florida — Gainesville, Florida, United States (enrolling)

Full record on ClinicalTrials.gov

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