Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer
Recruiting now · Not applicable
Conditions studied: Colonic Neoplasms
In brief
To goal of this clinical trial is to quantify the dose-response effects of aerobic exercise training compared to attention control on chemotherapy relative dose intensity in colon cancer survivors.
Key facts
- Study ID
- NCT05773144
- Run by
- AdventHealth Translational Research Institute
- People needed
- 219
- Starts
- 2023-06-01
- Expected to finish
- 2027-05-01
- Last updated by the study team
- 2026-01-07
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥18 years
- Histologically confirmed stage II or III colon cancer
- Completed surgical resection with curative intent
- Plan to initiate chemotherapy
- Engage in <60 minutes per week of moderate- to vigorous-intensity structured aerobic exercise
- No planned major surgery during the study period
- Readiness to exercise, as determined by a modified version of the Physical Activity Readiness Questionnaire
- Can walk 400 meters
- Can read and speak English
- Ability to provide written informed consent
- Provide written approval by qualified healthcare professional
- Willing to be randomized
You may not qualify if…
- Evidence of metastatic colon cancer
- Concurrently actively treated other (non-colon) cancer
- Currently pregnant, breastfeeding, or planning to become pregnant within the next 24 weeks
- Currently participating in another study with competing outcomes
- Any other condition that, in the opinion of the investigator, would preclude participation or successful compliance with the protocol
- Any other situation that, in the opinion of the investigator, would negatively impact subject safety or successful compliance with the protocol
Where it is running
- Kaiser Permanente Northern California — Oakland, California, United States (enrolling)
- AdventHealth — Orlando, Florida, United States (enrolling)
- Dana-Farber Cancer Institute — Boston, Massachusetts, United States (enrolling)
Full record on ClinicalTrials.gov
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