SGLT2 Inhibitors on Clinical Outcomes and Left Ventricular Remodeling in Type 2 Diabetic Patients with Acute Myocardial Infarction, a Prospective, Multi-center Registry Study
Recruiting now
Conditions studied: Myocardial Infarction, Diabetes Mellitus, Type 2
In brief
Prospective trials performed on type 2 diabetes patients without established cardiovascular disease has shown that SGLT2 inhibitors reduce cardiovascular risk. No studies have yet examined the occurrence of cardiovascular disease in patients with acute myocardial infarction. The investigators designed the current study to evaluate the most ideal oral hypoglycemic agent in type 2 diabetes patients undergoing percutaneous coronary intervention for acute myocardial infarction. The investigators hypothesize that the use of SGLT-2 inhibitors will reduce cardiovascular events and modify left ventricular remodeling after myocardial infarctions.
Key facts
- Study ID
- NCT05770687
- Run by
- Kiyuk Chang
- People needed
- 1000
- Starts
- 2020-08-01
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2025-01-03
Who can join
Age: 19 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Acute myocardial infarction who were treated with percutaneous coronary intervention
- Type 2 diabetes mellitus
- Started SGLT2 inhibitors <1 month before/after PCI
You may not qualify if…
- Type 1 diabetes mellitus
- Insulin / GLP-1 analogue users
- Previous users of SGLT2 inhibitors
- Pregnancy
Where it is running
- Seoul St. Mary's Hospital — Seoul, South Korea (enrolling)
Full record on ClinicalTrials.gov
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