Hyperpolarized 129Xe MRI Lung Health Cohort

Recruiting now

Conditions studied: Healthy

In brief

A subset of young adults participating in the American Lung Association (ALA) Lung Health Cohort (LHC) will be imaged using Hyperpolarized 129Xe MRI to assess lung structure and function. Images will be used to improve the understanding of lung health and early lung abnormalities that may lead to chronic lung disease.

Key facts

Study ID

NCT05766384

Run by

University of Kansas Medical Center

People needed

260

Starts

2023-11-30

Expected to finish

2027-03-31

Last updated by the study team

2026-05-01

Who can join

Age: 25 and older, up to 35. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Is enrolled in the American Lung Association Lung Health Cohort Study.
• Has completed CT imaging for the LHC study within 2 years of the scheduled Xe-MRI date.

You may not qualify if…

• Pacemaker, internal defibrillator or other implanted electronic devices or any standard MRI contraindications (e.g., claustrophobia, > 140 cm shoulder circumference, dependent on weight distribution).
• Is pregnant or breastfeeding
• Oxygen saturation (SpO2) <88% on room air or with supplemental oxygen.

Where it is running

• University of Iowa — Iowa City, Iowa, United States (enrolling)
• University of Kansas Medical Center — Kansas City, Kansas, United States (enrolling)
• Duke University — Durham, North Carolina, United States (enrolling)
• University of Illinois-Chicago — Chicago, Illinois, United States
• Baylor College of Medicine — Houston, Texas, United States
• MD Anderson Cancer Center — Houston, Texas, United States

Full record on ClinicalTrials.gov

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