External Body Pressure in Heart Failure With Preserved Ejection Fraction

Completed · Phase 1/Phase 2

Conditions studied: Heart Failure, Diastolic

In brief

The primary objective of the study is to test the impact of positive and negative body pressure on exercise capacity, symptoms, blood volume distribution and central cardiac hemodynamics in patients with heart failure and preserved ejection fraction. Aim 1 will study healthy volunteers and heart failure patients non invasively while Aim 2 will study heart failure patients invasively (intracardiac pressures).

Key facts

Study ID
NCT05764564
Run by
Duke University
People needed
27
Starts
2023-04-21
Expected to finish
2025-05-31
Last updated by the study team
2026-01-29

Who can join

Age: 30 and older. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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