Effects of RAS on Gait in PD Patients With DBS

Recruiting now · Not applicable

Conditions studied: Parkinson Disease

In brief

Participants will be asked to walk along with the metronome beats (RAS) during the participants' stimulation state (ON or OFF) for four minutes for each state. The researcher will collect the gait parameters (cadence, velocity, and stride length) of patients before, during, and after RAS in both DBS ON and OFF states. Using MDS-UPDRS, participants' gait patterns will be collected before and after RAS while both DBS is ON and OFF. Electrophysiological activity (local field potentials, LFPs) will be collected across all stages (pre, during, and post-RAS) of evaluation.

Key facts

Study ID

NCT05763732

Run by

Johns Hopkins University

People needed

10

Starts

2023-08-01

Expected to finish

2028-06-30

Last updated by the study team

2026-05-06

Who can join

Age: 18 and older, up to 89. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients diagnosed with Parkinson disease (PD) (and)
• PD patients who implanted Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) with PerceptTM PC

You may not qualify if…

• Inability or unwillingness to follow directions for study procedures

Where it is running

• Johns Hopkins School of Medicine — Baltimore, Maryland, United States (enrolling)

Full record on ClinicalTrials.gov

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