Uterine Junctional Zone and Its Relation to Adverse Obstetrical Outcomes in Assisted Reproductive Technology

Recruiting now

Conditions studied: Infertility, Female

In brief

The junctional zone (JZ) is an internal layer of the myometrium, with unique characteristics that allow its visualization as a hypoechogenic structure in three-dimensional (3D) ultrasound. While there is a growing realization that the origins of major obstetrical complications associated with defective deep placentation, such as pre-term labour, fetal growth restriction and pre-eclampsia, may lie in the very early pregnancy events, the underlying mechanisms are not understood.

Key facts

Study ID

NCT05763498

Run by

Centro Hospitalar Lisboa Norte

People needed

200

Starts

2023-02-24

Expected to finish

2025-07-31

Last updated by the study team

2024-08-20

Who can join

Age: 18 and older, up to 40. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Women followed in the infertility clinic aged between 18 and 42 years in cycles of IVF, ICSI or endometrial preparation for frozen embryo transfer

You may not qualify if…

• Myomas
• adenomyosis
• endometriosis

Where it is running

• Departamento de Obstetricia, Ginecologia e Medicina da Reprodução — Lisbon, Portugal (enrolling)
• Centro Hospitalar Universitário Lisboa Norte — Lisbon, Portugal (enrolling)
• Hospital Central do Funchal — Funchal, Madeira, Portugal

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.