Evaluation of Negative Inspiratory Flow in Children With Acute Asthma

Completed · Not applicable

Conditions studied: Asthma

In brief

There are different inhalers used for the treatment of asthma and they work differently and require different technique for the optimal drug delivery to the lungs. One of the inhalers is the Dry Powder Inhaler (DPI). The minimal amount of Negative Inspiratory Flow (NIF) required to use this medication is 30ml/min. Studies have shown that children find it difficult to generate this NIF and studies have also shown that children generate lesser NIF during an Asthma exacerbation. The investigators will measure the NIF using an InCheck Dial on children with asthma during an exacerbation and when they are seen in clinic for a hospital follow up visit. This will be done on asthmatic children regardless of the inhaler that they use. The investigator hypothesize that children with asthma age 4-8 years cannot generate the required NIF during an Asthma exacerbation hence proving that a DPI cannot be prescribed to children at this age. This study will examine this hypothesis.

Key facts

Study ID

NCT05762978

Run by

Winthrop University Hospital

People needed

7

Starts

2015-12-01

Expected to finish

2018-04-01

Last updated by the study team

2023-03-10

Who can join

Age: 4 and older, up to 8. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Hospitalized with asthma
• Age ≥ 4 years and < 8 years

You may not qualify if…

• Acute Lung Disease
• Chronic lung disease
• Developmental Delay

Where it is running

• Winthrop University Hospital — Mineola, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.