Blended Treatment för PTSD: A New Format of Computer-Assisted Trauma-Focused Cognitive Behavioral Therapy
Recruiting now · Not applicable
Conditions studied: PTSD, CBT
In brief
A Randomized Controlled Non-inferiority Trial testing if the new experimental Blended Trauma focused cognitive behavioral therapy (B-TF-CBT) for post traumatic stress disorder (PTSD), is non-inferior to gold standard control treatment Prolonged Exposure (PE). Research question and hypothesis Primary 1. Is bTF-CT non-inferior to prolonged exposure (PE) when delivered in routine clinical care in terms of PTSD symptoms on the PCL-5 post-treatment? Secondary: 2. Is bTF-CT non-inferior to prolonged exposure (PE) when delivered in routine clinical care in terms of PTSD symptoms on the PCL-5 at 6 and 12 months follow up? 3. Are there significant differences between bTF-CT and PE when delivered in routine clinical care in terms of depression, anxiety, insomnia, functionality, complex PTSD, other PTSD-measures and treatment satisfaction post-treatment and at 6 and 12 months follow up? The study will be conducted at 3-6 outpatient clinics in Region Stockholm, Sweden.
Key facts
- Study ID
- NCT05758987
- Run by
- Karolinska Institutet
- People needed
- 160
- Starts
- 2023-03-10
- Expected to finish
- 2027-10-10
- Last updated by the study team
- 2025-12-26
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- PTSD according to Diagnostic and Statistical Manual of mental disorders 5 as primary problem
- ≥ 18 years
- Basic knowledge of speaking and writing Swedish
- No other psychological treatment at the same time
- No ongoing threats or violence
- If antidepressant medication, stable dose 6 weeks before starting treatment
- Have access to the internet and a computer
- Willingness/ability to participate after receiving information about what participation entails
You may not qualify if…
- Other diagnosis or problem is assessed as primary to PTSD
- Moderate to severe suicidal risk
- PTSD from childhood trauma that the person cannot remember
Where it is running
- Karolinska Institutet — Stockholm, Sweden (enrolling)
Full record on ClinicalTrials.gov
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