Supporting Peer Interactions to Expand Access to Digital Cognitive Behavioral Therapy for Spanish-speaking Patients

Enrolling by invitation · Not applicable

Conditions studied: Depression, Anxiety

In brief

Investigators will evaluate the implementation of an evidence-based, Spanish-language, digital, cognitive-behavioral therapy intervention (SilverCloud) in primary care settings for Latino patients with depression and/or anxiety. 426 participants will be enrolled in a two-armed trial comparing self-guided vs. supported dCBT (SilverCloud). At the provider level, investigators will compare the efficacy of provider referrals with the use of a clinic patient registry to identify candidates who could benefit from a digital mental health intervention.

Key facts

Study ID

NCT05746767

Run by

University of California, Irvine

People needed

426

Starts

2024-03-14

Expected to finish

2028-03-31

Last updated by the study team

2026-05-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• PHQ-9 ≥ 10 or GAD-7 ≥ 8
• Has access to the Internet via smartphone and/or broadband at home, and basic level of technological literacy or willingness to undergo a brief technology use training
• ≥18 years of age
• Preference for receiving medical care in Spanish
• Not in concurrent psychotherapy
• If currently taking an antidepressant medication, patient must have been on a stable dose for at least 6 weeks, and have no plans to change the dose. We will permit patients on antidepressants to enter the study, as this will increase generalizability. Antidepressant status will be monitored at each assessment to control for those effects, if necessary.

You may not qualify if…

• Currently receiving psychotherapy, as this treatment will be offered as a frontline treatment for depression and anxiety, however, patients are allowed to be referred to treatment while participating in this study and initiation of treatment will be monitored and considered in analyses
• Visual, hearing, voice, or motor impairment or illiteracy that would prevent completion of study procedures
• Diagnosis of a psychotic disorder, bipolar disorder, dissociative disorder, or substance use disorder
• Severe suicidality (as assessed by expressing suicidal ideation, plan, and intent). Although procedures with back-up plans are in place for patients who develop suicidality (see Human Subjects Section), patients assessed with severe suicidality will be referred to more-intensive treatment resources.

Where it is running

• Payson Christian Clinic — Payson, Arizona, United States
• Family and Community Medicine Mobile Health Clinic — Tucson, Arizona, United States
• University of California — Berkeley, California, United States
• University of California — Irvine, California, United States
• Zuckerberg San Francisco General — San Francisco, California, United States
• Castro-Mission Health Center — San Francisco, California, United States
• Silver Avenue Family Health Center — San Francisco, California, United States
• UNMH North Valley Clinic — Albuquerque, New Mexico, United States
• Truman Health Clinic — Albuquerque, New Mexico, United States
• UNM Southeast Heights Clinic — Albuquerque, New Mexico, United States
• Sandoval Regional Medical Center — Rio Rancho, New Mexico, United States

Full record on ClinicalTrials.gov

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