The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion

Recruiting now · Phase 4 · Has a placebo group

Conditions studied: Spine Fusion, Lumbar Spine Degeneration, Pain, Postoperative, Lumbar Spine Spondylosis

In brief

The purpose of this study is to evaluate if peri-operative zolpidem for posterior lumbar spinal fusion improves patient reported outcomes following surgery.

Key facts

Study ID

NCT05746143

Run by

University of Southern California

People needed

140

Starts

2022-02-01

Expected to finish

2030-12-31

Last updated by the study team

2026-05-01

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• degenerative lumbar disease
• age of 18-75
• undergoing open primary one- to three-level lumbar fusion

You may not qualify if…

• currently use a sleep aid nightly
• diagnosed with insomnia or sleep apnea
• history of delirium with opiates or zolpidem
• allergic to opiates or zolpidem
• had previous lumbar spine surgery
• undergoing minimally invasive lumbar fusion,
• undergoing lumbar fusion for fracture, infection, tumor, or an inflammatory spondyloarthropathy

Where it is running

• Keck Medical Center of USC — Los Angeles, California, United States (enrolling)

Full record on ClinicalTrials.gov

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