A Long-term Extension Study to Evaluate Safety, Tolerability, and Efficacy of AL002 in Alzheimer's Disease

Stopped early · Phase 2

Conditions studied: Alzheimer's Disease

In brief

A long-term extension study to evaluate the safety, tolerability, and efficacy of AL002 in participants with Early Alzheimer's Disease.

Key facts

Study ID

NCT05744401

Run by

Alector Inc.

People needed

197

Starts

2023-01-04

Expected to finish

2025-02-05

Last updated by the study team

2026-02-25

Who can join

Age: 50 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Completion of the Planned Treatment Period in the AL002-2 study.
• The participant is willing and able to give informed consent.
• Study partner who consents to study participation and who cares for/visits the participant at least 10 hours a week

You may not qualify if…

• Participants deemed not able to provide consent or assent by the Investigator or by local regulations.
• Participants who were prematurely and permanently discontinued from treatment in the parent study for safety reasons.
• Participation deemed inappropriate per Investigator discretion.

Where it is running

• Georgetown University Medical Center — Washington D.C., District of Columbia, United States
• SFM Clinical Research, LLC — Boca Raton, Florida, United States
• Charter Research — Lady Lake, Florida, United States
• K2 Medical Research - Maitland — Maitland, Florida, United States
• Progressive Medical Research - ClinEdge - PPDS — Port Orange, Florida, United States
• Axiom Brain Health LLC — Tampa, Florida, United States
• "Alzheimers Research and Treatment Center-Wellington " — Wellington, Florida, United States
• Conquest Research LLC - Winter Park - ClinEdge - PPDS — Winter Park, Florida, United States
• Hattiesburg Clinic — Hattiesburg, Mississippi, United States
• Advanced Clinical Institute — Neptune City, New Jersey, United States
• Feinstein Institute For Medical Research — Manhasset, New York, United States
• SUNY Upstate Medical Center — Syracuse, New York, United States
• University of Cincinnati Medical Center — Cincinnati, Ohio, United States
• Summit Research Network — Portland, Oregon, United States
• Instituto Privado Kremer — Córdoba, Córdoba Province, Argentina
• Centro de Psiquiatria Biologica — Mendoza, Mendoza Province, Argentina
• KaRa Institute of Neurological Disease — Macquarie Park, New South Wales, Australia
• Box Hill Hospital — Box Hill, Victoria, Australia
• Alfred Health — Melbourne, Victoria, Australia
• Kawartha Regional Memory Clinic — Peterborough, Ontario, Canada
• Baycrest Health Sciences — Toronto, Ontario, Canada
• Universitätsklinikum Ulm-Oberer Eselsberg 45 — Ulm, Baden-Wurttemberg, Germany
• Klinikum rechts der Isar der Technischen Universitaet Muenchen — Munich, Bavaria, Germany
• Ambulantes Gesundheitszebtrum der Charite GmbH — Berlin, State of Berlin, Germany
• Banner Alzheimer's Institute — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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