Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis

Running, not enrolling · Phase 2

Conditions studied: Plaque Psoriasis

In brief

This is a multi-center, open-label extension (OLE) study in patients with plaque psoriasis who have completed their participation in a previous plaque psoriasis study of ESK-001.

Key facts

Study ID

NCT05739435

Run by

Alumis Inc

People needed

165

Starts

2023-01-17

Expected to finish

2027-12-31

Last updated by the study team

2026-07-28

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Must have completed a prior ESK-001 study
• Men and Women must use highly effective methods of contraception for the entirety of the study

You may not qualify if…

• Pregnancy
• Received a prohibited concomitant medication

Where it is running

• Investigator Site # 1029 — Birmingham, Alabama, United States
• Investigator Site #1001 — Phoenix, Arizona, United States
• Investigator Site # 1023 — Rogers, Arkansas, United States
• Investigator Site #1021 — Encinitas, California, United States
• Investigator Site #1018 — Los Angeles, California, United States
• Investigator Site #1007 — Santa Monica, California, United States
• Investigator Site #1002 — Sherman Oaks, California, United States
• Investigator site # 1030 — Fort Lauderdale, Florida, United States
• Investigator Site #1025 — Hialeah, Florida, United States
• Investigator site # 1028 — Miami, Florida, United States
• Investigator Site # 1013 — Tampa, Florida, United States
• Investigator Site #1035 — Macon, Georgia, United States
• Investigator Site #1043 — Sandy Springs, Georgia, United States
• Investigator Site #1005 — Rolling Meadows, Illinois, United States
• Investigator Site # 1011 — Columbus, Indiana, United States
• Investigator Site #1027 — South Bend, Indiana, United States
• Investigator SIte#1036 — Overland Park, Kansas, United States
• Investigator Site #1017 — Owensboro, Kentucky, United States
• Investigator Site #1026 — Rockville, Maryland, United States
• Investigator Site #1010 — Clarkston, Michigan, United States
• Investigator Site #1031 — New Brighton, Minnesota, United States
• Investigator Site #1033 — Norman, Oklahoma, United States
• Investigator Site #1019 — Portland, Oregon, United States
• Investigator Site #1022 — Philadelphia, Pennsylvania, United States
• Investigator Site # 1012 — Rapid City, South Dakota, United States

Full record on ClinicalTrials.gov

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