The Ambient Light Multiple Myeloma Study

Recruiting now · Not applicable

Conditions studied: Multiple Myeloma

In brief

The aim of this multi-site randomized control trial will be is to assess the impact Systematic lighting on circadian rhythm entrainment, Inflammation, Neutropenic Fever and Symptom Burden among Multiple Myeloma Patients undergoing Autologous Stem Cell Transplantation. To achieve this aim, 200 multiple myeloma patients will receive one of two different light-treatments that are designed to promote circadian rhythm alignment. While receiving these light treatments, participants' sleep efficiency, urine melatonin levels, blood inflammatory cytokine levels and symptoms will be assessed over a 2-month period.

Key facts

Study ID

NCT05737732

Run by

Icahn School of Medicine at Mount Sinai

People needed

200

Starts

2023-02-13

Expected to finish

2027-06-30

Last updated by the study team

2026-06-12

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Multiple Myeloma diagnosis
• Scheduled to undergo their first Autologous Stem Cell Transplant procedure.
• 21years or older
• Able to provide informed consent.
• English-language proficient

You may not qualify if…

• Previous Autologous Stem Cell Transplant procedure
• Pregnancy
• Eye diseases which limit the ability of light to be processed
• Secondary cancer diagnosis within the last 5 years
• Severe sleep disorders
• History of bipolar disorder or manic episodes
• Severe psychological impairment
• Previous use of light therapy
• Active infection including COVID-19 infection

Where it is running

• Icahn Schoool of Medicine at Mount Sinai — New York, New York, United States (enrolling)
• Memorial Sloan Kettering Cancer Center — New York, New York, United States (enrolling)

Full record on ClinicalTrials.gov

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