Effect of Magnesium Sulphate Pretreatment in Pediatric Abdominal Surgery

Recruiting now · Phase 2/Phase 3 · Has a placebo group

Conditions studied: Muscle Relaxation

In brief

In this study, the investigators will compare the effect of magnesium sulphate pretreatment on the onset and duration of intense and deep neuromuscular Block of rocuronium versus Cis-Atracurium and on the period of no response to nerve stimulation in children undergoing elective open abdominal surgeries.

Key facts

Study ID

NCT05736744

Run by

Assiut University

People needed

58

Starts

2023-06-20

Expected to finish

2025-12-01

Last updated by the study team

2025-01-20

Who can join

Age: 2 and older, up to 12. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age group 2-12 years old
• Both genders
• Children who will be scheduled to undergo elective laparoscopic surgeries.
• Patients with American Society of Anesthesiologist physical status classification of 1 or 2-

You may not qualify if…

• Patients who are beyond the selected age group.
• Patients on medications that interfered with muscle activity.
• Allergy to medications used in this study.
• Neuro-muscular diseases.
• Renal or hepatic impairment.
• Hypermagnesemia (>2.5 mmol) or hypomagnesemia (<1.7 mmol).
• Parental refusal to participate in the study

Where it is running

• Pediatric hospital, faculty of medicine, Assiut university — Asyut, Assiut Governorate, Egypt (enrolling)
• Pediatric hospital — Asyut, Assiut Governorate, Egypt (enrolling)

Full record on ClinicalTrials.gov

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