Impacts of Wild Blueberries on Appetite and Weight Regulation
Completed · Not applicable · Has a placebo group
Conditions studied: Obesity, Weight Loss
In brief
The objective is to complete a two-phase study to assess how wild blueberries impact regulation of appetite of overweight and obese men and women as well as to determine if wild blueberries can promote more effective weight loss than an isocaloric control. For phase I, the acute effects of consuming 1-cup of frozen wild blueberries mixed into ¾ C of low-fat yogurt will be compared to consuming an isocaloric serving of yogurt mixed with an artificially flavored and colored blueberry syrup. During acute testing, subjective ratings of appetite, glucose metabolism, and appetite-regulating hormones will be assessed. Phase II will consist of an 8-week feeding trial in which the same subjects will consume daily servings of yogurt mixed with either frozen wild blueberries or placebo syrup along with intensive counseling for weight loss. The hypothesis is that wild blueberries will reduce hunger by regulating appetite hormones and promoting beneficial glycemic and insulinemic responses and that daily consumption of wild blueberries will translate to improved adherence to a weight loss regimen and therefore greater weight and fat loss. Secondary aims for Phase II of this project will include exploring the impacts of blueberry consumption during weight loss on antioxidant status, inflammatory markers, blood lipid profiles, glucose status, dietary intake, physical activity and blood pressure.
Key facts
- Study ID
- NCT05736432
- Run by
- San Diego State University
- People needed
- 40
- Starts
- 2023-03-01
- Expected to finish
- 2025-02-01
- Last updated by the study team
- 2025-02-21
Who can join
Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Overweight or Obese (BMI 25-40)
You may not qualify if…
- Pregnancy
- Smoking
- >5 kg wt fluctuation in the past 3 months
- exercising > 2 times per week
- Medical conditions or medications that may affect body weight, metabolism, other outcome measures
- Allergy to blueberries or yogurt
- Already eating blueberries more than twice weekly
- Consumption of >50 g/d alcohol
Where it is running
- Mark Kern, PhD, RD — San Diego, California, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.