Genetics of Appendix Cancer Study

Recruiting now

Conditions studied: Appendix Cancer, Appendiceal Cancer, Appendiceal Neoplasms, Appendiceal Mucinous Neoplasm, Appendiceal Adenocarcinoma, Appendiceal Carcinoid Tumor, Appendiceal Neoplasm Malignant Secondary, Appendix Adenocarcinoma, Appendix Mucinous Neoplasm, Appendix Tumor, Appendix Cancer Metastatic, Appendix NET, Low-Grade Appendix Mucinous Neoplasm, High Grade Appendix Mucinous Neoplasm, High Grade Appendix Mucinous Adenocarcinoma

In brief

The GAP Study is a prospective cohort study designed to comprehensively investigate genetic variations that may contribute to cancer development among individuals diagnosed with appendix/appendiceal cancer who are ages 18+ years.

Key facts

Study ID: NCT05734430
Run by: Andreana Holowatyj, PhD, MSCI
People needed: 700
Starts: 2022-11-11
Expected to finish: 2034-11-01
Last updated by the study team: 2025-04-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

GAP Social
Known diagnosis of appendix cancer in the United States
Mentally and physically able to consent and participate in the study
GAP Vanderbilt
Known diagnosis of appendix cancer
Diagnosed by and/or consulting with a physician/clinical provider participating in the GAP Study
Mentally and physically able to consent and participate in the study
GAP Parent
Biological parents (mother and/or father) of individuals actively participating in the GAP Study
Residing in the United States
Mentally and physically able to consent and participate in the study

You may not qualify if…

Women pregnant at the time of consent
Prisoners
Unable to provide informed consent
Unable to read, write, or complete questionnaires in English

Where it is running

Vanderbilt-Ingram Cancer Center — Nashville, Tennessee, United States (enrolling)

Full record on ClinicalTrials.gov

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