Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients
Recruiting now · Not applicable
Conditions studied: Heart Transplant Rejection, Immune Suppression, Pediatric Heart Transplant, Medication Nonadherence, Health Behavior, Remote Monitoring, Patient Engagement
In brief
We will conduct a two-group randomized controlled trial to examine the eMocha DOT intervention with pediatric HT recipients.In this population, medication nonadherence remains a primary cause of late acute rejection (LAR) episodes, increased number of hospitalizations, graft failure, and patient mortality. Herein, we propose an innovative approach to promote medication adherence and improve patient and graft outcomes.
Key facts
- Study ID
- NCT05732779
- Run by
- University of Florida
- People needed
- 100
- Starts
- 2024-10-01
- Expected to finish
- 2027-05-01
- Last updated by the study team
- 2026-07-16
Who can join
Age: 10 and older, up to 21. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Eligible participants are 10-21 years of age
- Have received a heart transplant and are followed participating pediatric heart transplant centers
- English-speaking or Spanish-speaking
- Own a smart-phone or have access to the mobile app through other devices
- Are willing to receive information through it
- Have a MLVI score of greater than 2.0 over the last year
You may not qualify if…
- Those with cognitive impairments will not be eligible for enrollment due to inability to provide informed assent
Where it is running
- University of Miami, Miller School of Medicine — Coral Gables, Florida, United States (enrolling)
- University of Florida — Gainesville, Florida, United States (enrolling)
- Joe DiMaggio Children's Hospital — Hollywood, Florida, United States (enrolling)
- FSU College of Medicine — Tallahassee, Florida, United States
Full record on ClinicalTrials.gov
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