A Randomized Trial Comparing a Ventilatory Strategy To Prevent Atelectasis Versus a Lateral Decubitus Strategy During Robotic Bronchoscopy (VESPA vs. LADS Trial)
Running, not enrolling · Not applicable
Conditions studied: Pulmonary, Lung
In brief
To learn if LADS is better than VESPA at preventing atelectasis during a robotic bronchoscopy.
Key facts
- Study ID
- NCT05714033
- Run by
- M.D. Anderson Cancer Center
- People needed
- 62
- Starts
- 2023-02-10
- Expected to finish
- 2032-09-14
- Last updated by the study team
- 2026-04-15
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult patients (≥ 18 years old) undergoing diagnostic robotic bronchoscopy for a lung nodule suspicious for malignancy bronchoscopy under general anesthesia.
- Lung nodules should be up to 3 cm in diameter and located in right or left bronchial segments B2, B6, B9, and B10. Greater than 50% of the volume of the lesion needs to be below a horizontal line traced at the most anterior edge of the corresponding vertebral body.
- Chest CT performed < 45 days prior to bronchoscopy.
- Voluntary informed consent to participate in the study.
You may not qualify if…
- Patients with prior lung consolidation, interstitial changes or lung masses (> 3 cm in diameter) as seen on most recent CT
- Lesions outside of the designated lung areas defined as inclusion criteria.
- Known pregnancy
- Vulnerable population
- Ascites
- Known diaphragmatic paralysis
- Smokers or ex-smokers with known or suspected severe air-trapping defined as residual volume > 150% of predicted
- History of primary or secondary spontaneous pneumothorax
- Lung bullae > 5 cm
- Patients with mediastinal or hilar adenopathy with high suspicion for malignancy in whom lymph node sampling is indicated and should occur prior to robotic bronchoscopy of the peripheral lesion.
- Patient with active COVID pneumonia.
Where it is running
- M D Anderson Cancer Center — Houston, Texas, United States
Full record on ClinicalTrials.gov
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