Striated Esophageal Motor Function Modulation in Health and Disease

Recruiting now · Not applicable

Conditions studied: Dysphagia, Esophageal

In brief

The investigators hypothesize that striated esophagus deglutitive motor function is modulated by pharyngeal phase swallowing biomechanics.

Key facts

Study ID

NCT05708885

Run by

Medical College of Wisconsin

People needed

557

Starts

2022-09-13

Expected to finish

2027-04-01

Last updated by the study team

2026-05-05

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy subjects aged 18 to 90 years.
• Patents with dysphagia but normal high resolution esophageal manometric findings defined by the Chicago classification.

You may not qualify if…

• Anyone less than 18 years old.
• Patients with recent head and neck cancer (<1 month post-surgery or <3 months post-chemo radiation.
• Patients suffering from muscle diseases like muscular dystrophies, myopathies.
• Patients with neuro-muscular junction disorders myasthenia gravis, Eaton-Lambert disorders.
• Patients having history of allergy to lidocaine or barium.
• Patients who are pregnant or lactating.
• Patients who are medically unstable.
• Patients who are unable to apply the exerciser independently or with the help of a caregiver.
• Patients who lack cognition.

Where it is running

• Medical College of Wisconsin — Milwaukee, Wisconsin, United States (enrolling)

Full record on ClinicalTrials.gov

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