Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Disorder of Consciousness, Stroke
In brief
The goal of this clinical trial is to evaluate the efficacy of a musical interventionand non-invasive brain stimulation in neurological patients. The main questions it aims to answer are: * to evaluate the residual neuroplastic processes in DOC state related to music exposure * to determine the putative modulation of the aforementioned processes and the clinical outcome of DOC patients by non-pharmacological strategies, i.e., electric (tDCS) and music stimulation * to evaluate the impact of this intervention on caregiver's burden and psychological distress. Participants will be randomly assigned to one of three different music-listening intervention groups. Primary outcomes will be clinical, that is based on the neurologist's observations of clinical improvement, and neurophysiological, collected pre-intervention, post-intervention and post-placebo.
Key facts
- Study ID
- NCT05706831
- Run by
- Istituti Clinici Scientifici Maugeri SpA
- People needed
- 90
- Starts
- 2022-09-01
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2025-06-04
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age > 18 years
- Post-stroke aphasia
- Post-stroke neglect
- Patients with disorders of consciusness (DOC)
You may not qualify if…
- No auditory injury
- no hystory of neurological disease
- No hystory of psychiatric disease
- Previous stroke
- use of alcohol and drugs
- premorbid dementia
Where it is running
- Istituti Clinici Scientifici Maugeri — Bari, Ba, Italy (enrolling)
Full record on ClinicalTrials.gov
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