Cardiovascular and Cerebrovascular Control in Healthy Subjects

Recruiting now

Conditions studied: Healthy, Autonomic Nervous System, Cerebral Autoregulation

In brief

The aim of the study is to evaluate autonomic function and cerebrovascular control in 60 healthy subjects by means of noninvasive analysis of time series variability. To this extent, heart period, systolic and mean arterial blood pressure, cerebral blood velocity, peripheral resistances, respiration will be recorded from subjects during an orthostatic challenge. The interactions between autonomic cardiovascular function, cerebrovascular and peripheral control will be evaluated exploiting the most advanced signal processing techniques.

Key facts

Study ID

NCT05706532

Run by

IRCCS Policlinico S. Donato

People needed

60

Starts

2023-05-29

Expected to finish

2027-10-01

Last updated by the study team

2026-07-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• age >18
• sinus rhythm
• informed consent signed

You may not qualify if…

• age <18
• presence of autonomic nervous system diseases or dysfunctions

Where it is running

• IRCCS Policlinico San Donato — San Donato Milanese, Milan, Italy (enrolling)

Full record on ClinicalTrials.gov

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