Effects of Pitavastatin or Combination of Pitavastatin and Ezetimibe on Glucose Metabolism Compared to AtoRvastatin in atheroscLerotic Cardiovascular Disease Patients With Metabolic Syndrome: The EZ-PEARL Randomized Trial
Recruiting now · Not applicable
Conditions studied: Dyslipidemias, Atherosclerotic Cardiovascular Disease
In brief
The purpose of this study was to investigate the effect of pitavastatin or pitavastatin and ezetimibe combination therapy on glucose metabolism compared to atorvastatin in patients with atherosclerotic cardiovascular disease with metabolic syndrome.
Key facts
- Study ID
- NCT05705804
- Run by
- Yonsei University
- People needed
- 250
- Starts
- 2023-06-13
- Expected to finish
- 2027-06-01
- Last updated by the study team
- 2026-07-07
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with dyslipidemia
- Patient with diagnosis of clinical atherosclerotic cardiovascular disease (acute coronary syndrome, history of myocardial infarction, stable or unstable angina, history of coronary artery reperfusion, stroke or transient stroke, history of peripheral arterial disease or peripheral arterial reperfusion)
- Patients with metabolic syndrome but without diabetes
You may not qualify if…
- Diagnosis of clinical atherosclerotic cardiovascular disease within 1 year
- Acute liver disease or persistent unexplained serum AST or ALT three times the upper limit of normal
- Allergy or hypersensitivity to statins or ezetimibe
- Solid organ transplant recipients
- History of side effects requiring discontinuation of statin administration
- Pregnant women, potentially pregnant or lactating women
- Life expectancy less than 3 years
- If it is judged that follow-up for more than 1 year is not possible
- If the patient is unable to understand or read the consent form
Where it is running
- Yonsei University Health System, Severance Hospital — Seoul, South Korea (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.