Botswana Smoking and Abstinence Reinforcement Trial

Enrolling by invitation · Phase 4

Conditions studied: Smoking Cessation, Hiv

In brief

Many people living with HIV in southern Africa, specifically Botswana use tobacco products. Using tobacco makes some of the effects of HIV worse and even causes excess deaths. The investigators plan to use an intervention called Screening, Brief Intervention and Referral to Treatment (SBIRT) to help people to quit smoking and also a drug called varenicline. Apart from helping people to stop smoking, the investigators will also test to see how task shifting can be used to help people stop smoking in a sustainable way. Finally, the investigators will estimate the cost of the intervention.

Key facts

Study ID

NCT05694637

Run by

University of Maryland, Baltimore

People needed

750

Starts

2023-07-25

Expected to finish

2027-08-31

Last updated by the study team

2026-01-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• HIV infected
• Self reported current daily smoker
• Age 18 and older
• Engaged in HIV care as defined by being on ART for at least 6 months
• Willing/able to provide informed consent in English or Setswana

You may not qualify if…

• Less than 18 years of age
• Pregnant
• Unable or cognitively impaired to provide consent

Where it is running

• Itekeng Clinic — Francistown, Central District, Botswana
• Masego Clinic — Francistown, Central District, Botswana
• Nyangabgwe Referral Hospital — Francistown, Central District, Botswana
• Airstrip Clinic — Mahalapye, Central District, Botswana
• Mahalapye District Hospital — Mahalapye, Central District, Botswana
• Morwa Clinic — Mochudi, Central District, Botswana
• Palpye Primary Hospital — Palapye, Central District, Botswana
• Sefhare Primary Hospital — Sefhare, Central District, Botswana
• Tutume Primary Hospital — Tutume, Central District, Botswana
• Thamaga Primary Hospital — Thamaga, Kweneng District, Botswana
• Goodhope Primary Hospital — Good Hope, Botswana
• Kanye Adventist Hospital — Kanye, Botswana
• Kediretswe Clinic — Palapye, Botswana
• Sekgoma District Hospital — Serowe, Botswana
• Serowe Clinic — Serowe, Botswana

Full record on ClinicalTrials.gov

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