A Study of Participants With Chronic Kidney Disease Previously Treated With REACT

Stopped early · Phase 1

Conditions studied: Diabetic Kidney Disease, CAKUT, Chronic Kidney Diseases

In brief

The purpose of this study is to evaluate the safety of supplemental REACT injections in participants with chronic kidney disease (CKD) who have previously received REACT treatment.

Key facts

Study ID

NCT05694169

Run by

Prokidney

People needed

1

Starts

2023-07-11

Expected to finish

2024-05-13

Last updated by the study team

2025-02-28

Who can join

Age: 30 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• The participant has received REACT in a previous trial for treatment of chronic kidney disease and completed their parent protocol follow up period.
• The participant is male or female, 30 to 80 years of age on the date of informed consent.
• The participant has a documented clinical diagnosis of an eGFR greater than or equal to 14 and less than or equal to 50 mL/min/1.73m2, not requiring renal dialysis.
• The participant has stable blood pressure and is maintained on a stable antihypertensive medication regimen if treatment for hypertension is necessary.

You may not qualify if…

• The participant has a history of renal transplantation.
• The participant has received dialysis for more than 30 days.
• The participant has received any other investigational products after completion of REACT injections within 3 months of screening.
• The participant has a urinary albumin-to-creatinine ratio (UACR) of greater than 5,000 mg/g.
• The participant has hemoglobin levels less than 10 g/dL and is not responsive to the standard medical intervention for CKD-related anemia prior to screening.

Where it is running

• Boise kidney and Hypertension Institute — Boise, Idaho, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.