Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms

Recruiting now

Conditions studied: Alcohol Drinking, Alcohol Intoxication

In brief

The study will employ a combined laboratory-ambulatory design. Participants will engage in ambulatory assessment over the course of 14 days, wearing biosensors assessing transdermal alcohol concentration (TAC) and providing breathalyzer readings in real-world contexts. Also during this period, participants will attend three laboratory alcohol-administration sessions scheduled at one-week intervals, with alcohol dose and rate of consumption manipulated within and between participants, respectively. Laboratory visits will also double as ambulatory orientation, check-in, and close-out sessions.

Key facts

Study ID

NCT05692830

Run by

University of Illinois at Urbana-Champaign

People needed

240

Starts

2022-10-22

Expected to finish

2027-09-01

Last updated by the study team

2025-08-06

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 21 years or older
• drink alcohol at least 2x weekly

You may not qualify if…

• psychological or medical conditions that might contraindicate alcohol-administration
• history of adverse reaction to type and amount of beverage used in the study
• currently seeking treatment for alcohol use disorder
• does not drink alcohol regularly
• taking drugs or medications for which alcohol consumption would be contraindicated
• women who are pregnant or are attempting to become pregnant

Where it is running

• University of Illinois at Urbana-Champaign — Champaign, Illinois, United States (enrolling)

Full record on ClinicalTrials.gov

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