Psychosocial Mobile App for Chronic Graft-Versus-Host Disease

Running, not enrolling · Not applicable

Conditions studied: Chronic Graft-Versus-Host Disease, Allogeneic Stem Cell Transplant

In brief

The purpose of this research study is to see whether a psychosocial mobile app called Horizons is effective at improving quality of life, symptom burden, psychological distress, and coping in patients living with chronic graft-versus host disease (GVHD)

Key facts

Study ID

NCT05690971

Run by

Massachusetts General Hospital

People needed

120

Starts

2023-01-23

Expected to finish

2027-06-01

Last updated by the study team

2026-07-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients (≥18 years) who underwent allogeneic hematopoietic stem cell transplant (HCT).
• Have moderate to severe chronic GVHD based on their oncology clinician assessment as documented in the Electronic Health Record.
• Ability to comprehend and speak English as the HORIZONs app is only available in English.

You may not qualify if…

• Patients with acute or unstable psychiatric or cognitive conditions which the treating clinicians believes prohibits informed consent or compliance with study procedures.

Where it is running

• Massachusetts General Hospital Cancer Center — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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