Usefulness of PET-CT for Invasive Fungal Infection
Recruiting now
Conditions studied: Invasive Fungal Infections
In brief
The goal of this national multicenter prospective cohort study is to learn about the added value of 18F-FDG (18F-2-fluoro-2-deoxy-D-glucose) PET-CT in invasive fungal disease management. The main questions it aims to answer are: 1. Does the use of 18F-FDG PET-CT allow a better characterization of invasive fungal infection (IFI) (performance) compared to the exclusive use of conventional radiological studies in terms of extension/staging and monitoring of response/follow-up ? 2. Does the systematic and protocolized use of 18F-FDG PET-CT in IFI allow a better management of patients with IFI and increase the prognostic value of the initial evaluation? Participants will undergo systematically a 18F-FDG PET-CT as part of the work-up of their invasive fungal disease. Researchers will compare the performance of 18F-FDG PET-CT with standard management without 18F-FDG PET-CT to see if adds value (diagnostic, prognostic, and changes in management).
Key facts
- Study ID
- NCT05688592
- Run by
- Puerta de Hierro University Hospital
- People needed
- 224
- Starts
- 2023-04-27
- Expected to finish
- 2024-12-01
- Last updated by the study team
- 2024-11-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- 18-year-old adult patients
- who are admitted with a diagnosis of invasive fungal infection
- who able to undergo a one 18F-FDG PET-CT
- who give their informed consent.
You may not qualify if…
- concomitant active bacterial infection likely to produce uptake in organs and tissues
- recent surgery in the area of the IFI (in the previous 3 months)
- other medical conditions that interfere with the development of the study ( e.g., inability to tolerate the performance of the test during the required time, pregnancy)
- terminal situation.
Where it is running
- Hospital Universitario Virgenn de la Macarena — Seville, Spain (enrolling)
- Hospital de Bellvitge — Barcelona, Spain (enrolling)
- Hospital Universitario Clinic — Barcelona, Spain (enrolling)
- Hospital Universitario Virgen de las Nieves — Granada, Spain (enrolling)
- Hospital Infanta Leonor Hospital — Madrid, Spain (enrolling)
- Hospital Universitario Gregorio Marañón — Madrid, Spain (enrolling)
- Hospital Universitario La Paz — Madrid, Spain (enrolling)
- Hospital Unversitario Ramón y Cajal — Madrid, Spain (enrolling)
- Hospital Virgen de la Victoria — Málaga, Spain (enrolling)
- Hospital Unversitario de Salamanca — Salamanca, Spain (enrolling)
- Hospital Universitario Puerta de Hierro — Majadahonda, Madriid, Spain (enrolling)
- Hospital Universitario Central de Asturias — Oviedo, Spain (enrolling)
- Hospital Morales Messeguer — Murcia, Spain
- Hospital Virgen de la Arrixaca — Murcia, Spain
Full record on ClinicalTrials.gov
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