Intensive Postpartum Antihypertensive Treatment

Running, not enrolling · Phase 3

Conditions studied: Hypertensive Disorder of Pregnancy

In brief

The long-term goal of our work is to evaluate the effect of intensive postpartum blood pressure control on maternal cardiovascular health, risk of chronic hypertension, and reversal of vascular dysfunction generated by hypertensive disorders of pregnancy, thus attenuating the lifelong trajectory of cardiovascular disease risk.

Key facts

Study ID

NCT05687344

Run by

Medical College of Wisconsin

People needed

60

Starts

2023-09-01

Expected to finish

2026-08-30

Last updated by the study team

2026-07-20

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• HDP diagnosis (gestational hypertension or preeclampsia) according to ACOG guidelines
• Postpartum day 0-3 and prior to discharge
• Able to communicate in English or in Spanish
• Age 18 - 45

You may not qualify if…

• Pre-gestational hypertension
• Pre-gestational diabetes ( type 1 or type 2)
• Intent to transfer postpartum to an outside institution of the participating centers
• Known allergy to nifedipine or other significant contraindication to nifedipine
• Inability or unwillingness to provide informed consent

Where it is running

• Froedtert Hospital — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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