Application of a Clinical Decision Support System to Reduce Mechanical Ventilation Duration After Cardiac Surgery in Children

Recruiting now

Conditions studied: Congenital Heart Disease

In brief

The goal of this study is to evaluate the impact of a clinical decision support system (CDSS) in children receiving mechanical ventilation (MV) after surgery for congenital heart disease (CHD). The main question it aims to answer is: -What is the impact of a CDSS designed to facilitate weaning and discontinuation of MV on the duration of MV in post-operative congenital cardiac surgery patients? Participants will be identified as eligible to initiate weaning from mechanical ventilation. Providers will decide whether or not to initiate weaning based on recommendations provided by the CDSS. Researchers will compare patients exposed to the CDSS with a historical cohort to see if the CDSS facilitated a decrease in MV duration.

Key facts

Study ID

NCT05687292

Run by

Boston Children's Hospital

People needed

330

Starts

2024-11-18

Expected to finish

2027-03-01

Last updated by the study team

2026-05-12

Who can join

Age: 0 and older, up to 12. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Children < 12 years old
• Post-cardiac surgery
• Receiving mechanical ventilation for ≥ 48 hours in the Cardiac Intensive Care Unit at Boston Children's Hospital following surgery

You may not qualify if…

• Premature infants (<37 weeks' gestation)
• Weight < 2kg
• Baseline ventilator (via tracheostomy) or noninvasive positive pressure dependence

Where it is running

• Boston Children's Hospital — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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