Perioperative Immunonutrition Intervention and Oral Decontamination in Elderly Surgical Patients
Recruiting now · Not applicable
Conditions studied: Postoperative Complications
In brief
Elderly patients are vulnerable to postoperative complications. Preoperative malnutrition and poor oral hygiene are risk factors for postoperative complications especially pulmonary complications. This study aims to investigate the feasibility and efficacy of perioperative oral decontamination and immunonutrition supplement on reducing postoperative complications in elderly surgical patients.
Key facts
- Study ID
- NCT05679661
- Run by
- Huang YuGuang
- People needed
- 590
- Starts
- 2023-02-06
- Expected to finish
- 2026-01-01
- Last updated by the study team
- 2025-03-03
Who can join
Age: 65 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- age≥65 years;
- undergoing non-cardiac surgery (expected duration >2 hours);
- scheduled for general anesthesia and endotracheal intubation;
- ASA classification I-IV;
- with intermediate to high risk of respiratory complications assessed by ARISCAT score (Assess Respiratory Risk in Surgical Patients in Catalonia);
- inform consent obtained
You may not qualify if…
- emergency surgery;
- preoperative pneumonia;
- allergic to chlorhexidine;
- severe hepatic/renal dysfunction, incapable of oral feeding, with autoimmune diseases, taking immunosuppressant or immunoregulation medications, or with other contraindication to immunonutrition supplementation;
- expected intervention of immunonutrition<3 days.
Where it is running
- Peking Union Medical College Hospital — Beijing, China (enrolling)
Full record on ClinicalTrials.gov
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