Role of Paclitaxel in Stricture Urethra

Recruiting now · Not applicable

Conditions studied: Stricture Urethra

In brief

Stricture urethra is a common disease and has various causing factors. The most common performed procedure is direct visual internal urethrotomy (DVIU), but unfortunately has a high recurrence rates. Multiple trial were performed to improve the outcomes of DVIU. Various intralesional injections were used. in this trial we will evaluate intralesional paclitaxel injection following DVIU.

Key facts

Study ID

NCT05678413

Run by

Al-Azhar University

People needed

200

Starts

2022-06-01

Expected to finish

2025-10-01

Last updated by the study team

2024-08-15

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Anterior urethral stricture
• Short strictures (less than 2 cm)
• International Prostate Symptom Score less than 11 and maximum flow rate < 15 ml per second.
• No previous treatment for stricture disease

You may not qualify if…

• Recurrent cases
• Prior pelvic radiation
• Associated other pathology or unresolved confounding etiologies (e.g. bladder neck contracture, neurogenic bladder, benign prostatic hyperplasia) were excluded.

Where it is running

• Mohamed Fawzy Salman — Cairo, Egypt (enrolling)

Full record on ClinicalTrials.gov

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