Feedback Loop Between Intracranial Atherosclerosis and Cerebral Small Vessel Disease

Recruiting now

Conditions studied: ICAS - Intracranial Atherosclerosis, Cerebral Small Vessel Diseases

In brief

The present study aims at verifying the mutual effects between intracranial large artery atherosclerosis and cerebral small vessel disease on disease progression and prognosis by magnetic resonance imaging, and providing biomarkers for the early prevention and treatment of cerebrovascular disease.

Key facts

Study ID

NCT05677607

Run by

Chinese PLA General Hospital

People needed

300

Starts

2023-01-01

Expected to finish

2027-12-31

Last updated by the study team

2024-07-03

Who can join

Age: 30 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years
• At least one intracranial artery ≥ 50% atherosclerotic stenosis
• Modified Rankin Scale < 2
• Mini-mental State Examination > 24

You may not qualify if…

• Concurrent ipsilateral extracranial artery ≥ 50% stenosis
• Pregnant women
• Contraindications to magnetic resonance examination (patients with pacemakers, nerve stimulators, artificial metal heart valves and other metal foreign bodies)

Where it is running

• Chinese PLA General Hospital — Beijing, Beijing Municipality, China (enrolling)

Full record on ClinicalTrials.gov

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