Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Recruiting now · Not applicable
Conditions studied: Heart Failure, Cardiorenal Syndrome, Cardio-Renal Syndrome, ADHF, Heart Failure, Systolic, Heart Failure, Diastolic, Heart Failure; With Decompensation, Heart Failure, Congestive
In brief
Aortix is a circulatory support device for chronic heart failure patients on medical management who have been hospitalized for acute decompensated heart failure (ADHF) and have persistent congestion despite usual medical therapy. Eligible ADHF patients with diuretic resistance (irrespective of ejection fraction) will be enrolled and randomized 1:1 to either the Aortix system or standard of care medical management.
Key facts
- Study ID
- NCT05677100
- Run by
- Procyrion
- People needed
- 320
- Starts
- 2023-08-23
- Expected to finish
- 2028-08-01
- Last updated by the study team
- 2026-08-04
Who can join
Age: 21 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Oklahoma Cardiovascular Research Group — Oklahoma City, Oklahoma, United States (enrolling)
- Mayo Clinic - Arizona — Phoenix, Arizona, United States (enrolling)
- University of Mississippi Medical Center — Jackson, Mississippi, United States (enrolling)
- Hackensack University Medical Center — Hackensack, New Jersey, United States (enrolling)
- Jersey Shore University Medical Center — Neptune City, New Jersey, United States (enrolling)
- New York Presbyterian - Brooklyn Methodist Hospital — Brooklyn, New York, United States (enrolling)
- Mount Sinai Morningside — New York, New York, United States (enrolling)
- Nyph/Cumc — New York, New York, United States (enrolling)
- Nuvance Health — Poughkeepsie, New York, United States (enrolling)
- Northwell Health (Staten Island) — Staten Island, New York, United States (enrolling)
- Atrium Health Sanger Heart and Vascular Institute — Charlotte, North Carolina, United States (enrolling)
- The Ohio State University — Columbus, Ohio, United States (enrolling)
- Banner--University Medical Center Phoenix — Phoenix, Arizona, United States (enrolling)
- Jefferson Abington Hospital — Abington, Pennsylvania, United States (enrolling)
- Penn Presbyterian Medical Center — Philadelphia, Pennsylvania, United States (enrolling)
- AnMed Health — Anderson, South Carolina, United States (enrolling)
- Texas Heart Institute — Houston, Texas, United States (enrolling)
- Virginia Commonwealth University — Richmond, Virginia, United States (enrolling)
- Semmelweis University — Budapest, Hungary (enrolling)
- John Muir Health — Concord, California, United States (enrolling)
- Zuckerberg San Francisco General — San Francisco, California, United States (enrolling)
- University of California San Francisco — San Francisco, California, United States (enrolling)
- University of South Florida — Tampa, Florida, United States (enrolling)
- BayCare Medical/St. Joseph's Hospital — Tampa, Florida, United States (enrolling)
- AdventHealth Tampa — Tampa, Florida, United States (enrolling)
Full record on ClinicalTrials.gov
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