Confirmation of Diet as a Treatment for Gulf War Illness
Status unconfirmed · Phase 3
Conditions studied: Gulf War Syndrome, Gulf War Illness
In brief
This clinical trial aims to confirm previous findings from a smaller study which demonstrated significant improvements in all symptoms among veterans with Gulf War Illness after one month on the dietary intervention. The main objectives of this study are: 1) to confirm previous findings of treatment response to the diet in a larger and more diverse group; 2) to examine how changes in the nervous system may be the reason for improvement; and 3) to identify markers which change in the blood after one month on the diet. Participants will have baseline measures collected and then will be randomized into the intervention or wait-listed control group, which they will follow for one month before being reassessed.
Key facts
- Study ID
- NCT05675878
- Run by
- American University
- People needed
- 160
- Starts
- 2023-03-01
- Expected to finish
- 2025-12-30
- Last updated by the study team
- 2024-07-09
Who can join
Age: 50 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Males and Females of all races and ethnicities who are ≤75 yrs of age
- Served in the 1990-1991 Persian Gulf War
- Fulfill both Center for Disease Control (CDC) and Kansas definitions of Gulf War Illness
- Stable medication regimen for ≥1 month and willing to keep medications and supplements stable throughout study participation
You may not qualify if…
- Recent substance use disorder (past year)
- Unwilling to stop using alcohol, tobacco (including vaping) and/or marijuana; or unwilling to change diet
- Diagnosed seizure disorder or severe asthma requiring past hospitalization
- Currently taking medication which affects glutamatergic or GABAergic neurotransmission (but can work with their physician to wean off of these medications prior to participating)
Where it is running
- American University — Washington D.C., District of Columbia, United States (enrolling)
- Nova Southeastern University — Fort Lauderdale, Florida, United States (enrolling)
- Boston University — Boston, Massachusetts, United States (enrolling)
Full record on ClinicalTrials.gov
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