Brain Stimulation and Meditation for Pain After Total Knee Arthroplasty

Completed · Not applicable · Has a placebo group

Conditions studied: Osteoarthritis, Knee

In brief

Feasibility, acceptability, and preliminary efficacy of combined transcranial direct current stimulation and mindfulness for pain after total knee arthroplasty

Key facts

Study ID

NCT05673720

Run by

Florida State University

People needed

24

Starts

2023-05-15

Expected to finish

2024-10-25

Last updated by the study team

2025-11-24

Who can join

Age: 50 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• elective unilateral knee total replacement
• mentally capable of reading, giving consent and following instructions
• being able to answer questions in English
• not pregnant

You may not qualify if…

• history of brain surgery, brain tumor, seizure, stroke, or intracranial metal implantation
• systemic rheumatic disorders, including rheumatoid arthritis, systemic lupus erythematosus, and fibromyalgia
• alcohol/substance abuse
• current use of sodium channel blockers, calcium channel blockers and NMDS receptor antagonists
• hospitalization within the preceding year for psychiatric illness
• no access to a device with internet access that can be used for secure videoconferencing for real-time remote supervision

Where it is running

• Tallahassee Orthopedic Clinic — Tallahassee, Florida, United States

Full record on ClinicalTrials.gov

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