Neural Pressure Support, Synchrony and Respiratory Muscle Unloading

Recruiting now · Not applicable

Conditions studied: Acute Respiratory Failure

In brief

In this study patients who are intubated and on ventilator for more than 24h will be ventilated at three different level of support in Pressure Support and Neural Pressure Support to study patient-ventilator synchrony and muscle unloading.

Key facts

Study ID

NCT05670093

Run by

Karolinska Institutet

People needed

22

Starts

2022-05-17

Expected to finish

2026-06-01

Last updated by the study team

2024-09-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients intubated for more than 24 hours in the weaning phase from the ventilator.

You may not qualify if…

• bleeding disorders (PK INR>1,5 or APTT>50s or platelet count <50000/µL)
• unstable circulation (requiring high vasopressor dose, for example Noradrenalin >0,2µg/kg/min)
• severe lung disease (PFI ≤ 13,3 kPa)
• fever> 38,5°C
• pregnancy.

Where it is running

• Karolinska University Hospital — Solna, Sweden (enrolling)

Full record on ClinicalTrials.gov

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