Mucograft Seal in ARP Follow-up
Recruiting now
Conditions studied: Dental Implant
In brief
Rationale: Early implant placement with alveolar ridge preservation (ARP) using either a collagen matrix or a palatal graft rendered similar esthetic, clinical and PROMs to early implant placement without ARP, up to 1 year after functional loading. Objective: The aim of this study is to evaluate esthetic and clinical outcomes and patient satisfaction following single-tooth replacement in the anterior maxilla in patients treated with a xenograft and a collagen matrix or a free connective tissue graft versus spontaneous healing 5 years after loading Study design: prospective observational study with 5-year follow-up Intervention (if applicable): not applicable Main study parameters/endpoints: Comparison of the level of the buccal marginal gingiva (midfacial mucosa level) between ARP versus spontaneous healing Secondary parameters/endpoint: Peri-implant esthetic score (PES) and white esthetic score (WES), complications, implant survival; and success, Plaque Index, Modified bleeding index, Gingival Index, Probing Depth, PROMs, bone and soft tissue volumetric dimensional changes.
Key facts
- Study ID
- NCT05663385
- Run by
- Erasmus Medical Center
- People needed
- 75
- Starts
- 2024-04-16
- Expected to finish
- 2025-10-01
- Last updated by the study team
- 2025-08-12
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- All patients previously included in the above mentioned RCT.
You may not qualify if…
- Patients treated with radiotherapy during follow-up in the head-and-neck region or current chemotherapy; disability (mental and/or physical) to maintain basic oral hygiene procedures.
Where it is running
- Erasmus Mc — Rotterdam, Netherlands (enrolling)
Full record on ClinicalTrials.gov
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