The Effects of Using Different Anesthetics on the Prognosis of Primary Lung Tumors and Its Mechanism of Action

Recruiting now · Phase 4

Conditions studied: Lung Cancer, Progression, Disease, Anesthesia

In brief

This is a two-arm, parallel-group randomized clinical trial. Routine perioperative care would be performed in volunteers with primary early lung cancer. The study will enroll approximately 300 volunteers to compare the progression-free or overall survival in patients undergoing video-assisted thoracoscopic surgery (VATS) for primary lung tumors between propofol and sevoflurane for the maintenance of anesthesia.

Key facts

Study ID

NCT05663242

Run by

Kaohsiung Medical University Chung-Ho Memorial Hospital

People needed

300

Starts

2022-12-27

Expected to finish

2026-11-30

Last updated by the study team

2023-05-30

Who can join

Age: 20 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• eighteen to eighty-year-old
• ASA class I-III patients
• Received elective thoracic surgery for primary lung tumors under general anesthesia

You may not qualify if…

• mental disorder
• poor liver function
• pregnant or lactating women
• morbidly obese
• allergy to any of the drugs used in this study
• recurrent tumor or repeat surgery
• biopsy cases
• incomplete outcome-data
• palliative treatment after surgery
• simultaneous treatment of other malignancies
• emergency surgery
• presence of other malignant tumors
• combined propofol and inhalation anesthesia or other anesthetics, such as ketamine or dexmedetomidine
• diagnosed as benign lung tumor, or other metastatic lung tumor

Where it is running

• Kaohsiung Medical University Chung-Ho Memorial Hospital — Kaohsiung City, Taiwan (enrolling)

Full record on ClinicalTrials.gov

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