Adaptive Trial Scheduling in Naming Treatment for Aphasia

Recruiting now · Phase 2

Conditions studied: Aphasia, Stroke

In brief

Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of life. Anomia (i.e., word- finding difficulty) is a primary frustration for people with aphasia. Picture-based naming treatments for anomia are widely used in aphasia rehabilitation, but current treatment approaches do not address the long-term retention of naming abilities and do not focus on using these naming abilities in daily life. The current research aims to evaluate novel anomia treatment approaches to improve long-term retention and generalization to everyday life. This study is one of two that are part of a larger grant. This record is for sub-study 2, which will evaluate the benefits of adaptive trial spacing.

Key facts

Study ID

NCT05653466

Run by

University of Pittsburgh

People needed

32

Starts

2023-12-06

Expected to finish

2028-01-31

Last updated by the study team

2025-12-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Existing diagnosis of chronic (>6 months) aphasia subsequent to left hemisphere stroke.
• Impaired performance on 2/8 sections of the Comprehensive Aphasia Test.
• Must have access to a high-speed internet connection and be able to participate in telehealth.

You may not qualify if…

• History of other acquired or progressive neurological disease.
• Significant language comprehension impairments
• Unmanaged drug / alcohol dependence.
• Severe diagnosed mood or behavioral disorders that require specialize mental health interventions.

Where it is running

• Language Rehab and Cognition Lab, Department of Communication Sciences and Disorders, School of Health and Rehabilitation Sciences, University of Pittsburgh — Pittsburgh, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

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