ACE1831 in Adult Subjects With Relapsed/ Refractory CD20-expressing B-cell Malignancies
Completed · Phase 1
Conditions studied: B-cell Lymphoma, Non Hodgkin Lymphoma, DLBCL, Primary Mediastinal Large B Cell Lymphoma, Marginal Zone Lymphoma, Follicular Lymphoma, Burkitt Lymphoma, High-grade B-cell Lymphoma
In brief
ACE1831 is an off-the-shelf, allogeneic gamma delta T (gdT) cell therapy derived from healthy donors, that is under investigation for the treatment of CD20-expressing B-cell malignancies. The ACE1831-001 study is an open-label, Phase I, first-in-human (FIH) study that aims to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics, and efficacy of ACE1831 in patients with CD20-expressing Non-Hodgkin lymphoma.
Key facts
- Study ID
- NCT05653271
- Run by
- Acepodia Biotech, Inc.
- People needed
- 16
- Starts
- 2023-01-21
- Expected to finish
- 2026-03-31
- Last updated by the study team
- 2026-06-30
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- AdventHealth Orlando — Orlando, Florida, United States
- Emory University — Atlanta, Georgia, United States
- Indiana University Simon Comprehensive Cancer Center — Indianapolis, Indiana, United States
- Norton Cancer Institute — Louisville, Kentucky, United States
- The University of Texas MD Anderson Cancer Center — Houston, Texas, United States
- Queen Mary Hospital — Hong Kong, Hong Kong, Hong Kong
- Kaohsiung Chang-Gung Memorial Hospital — Kaohsiung City, Kaohsiung, Taiwan
- National Cheng Kung University Hospital — Tainan, Tainan, Taiwan
- National Taiwan University Hospital — Taipei, Taipei, Taiwan
- Ministry of Health and Welfare Shuang-Ho Hospital — New Taipei City, Taiwan, Taiwan
- Taichung Veterans General Hospital — Taichung, Taiwan, Taiwan
- Tamsui MacKay Memorial Hospital — New Taipei City, Taiwan
- Linkou Chang-Gung Memorial Hospital — Taoyuan City, Taiwan
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.