The CALERIE™ Legacy Study

Running, not enrolling

Conditions studied: Calorie Restriction

In brief

The purpose of the CALERIE Legacy Study is to follow up on the health and wellness of participants from phase 2 of the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE) trial, which was conducted from 2007 to 2011.

Key facts

Study ID

NCT05651620

Run by

Tufts University

People needed

216

Starts

2023-04-06

Expected to finish

2028-01-31

Last updated by the study team

2026-06-09

Who can join

Age: 33 and older, up to 70. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Enrolled in the CALERIE trial and started their allocated group (CR intervention or ad libitum control condition)
• Willing and able to attend one of the clinical sites for an in-person visit and provide informed consent

You may not qualify if…

• Pregnant women
• Women less than 12 months postpartum
• Documented note from the CALERIE trial indicating that the subject should not be contacted or requested not to be contacted for future research
• Diagnosed active cancer or terminal illness

Where it is running

• Pennington Biomedical Research Center — Baton Rouge, Louisiana, United States
• Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University — Boston, Massachusetts, United States
• Washington University School of Medicine — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.