A Precision Medicine Approach to Target Engagement for Emotion Regulation

Recruiting now · Not applicable

Conditions studied: Emotional Regulation, Depression, Anxiety, Borderline Personality Disorder, Obsessive-Compulsive Disorder, Posttraumatic Stress Disorder, Eating Disorders

In brief

The proposed study is designed to first test whether teaching people personalized or standardized emotion regulation skills leads to greater decreases in daily negative emotion intensity. Second, using data from an initial sample, the investigators will prospectively assign an independent sample of participants to receive their predicted optimal or non-optimal skills to determine if it is feasible and efficacious to match participants to the most appropriate training condition. Results of these studies may identify the mechanisms by which emotion regulation interventions impact emotional functioning and allow for the development of personalized, evidence-based, and scalable emotion regulation interventions.

Key facts

Study ID

NCT05651295

Run by

Matthew Southward, PhD

People needed

390

Starts

2023-09-29

Expected to finish

2026-12-31

Last updated by the study team

2026-05-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Elevated emotion dysregulation

You may not qualify if…

• Lack of proficiency in English
• No access to smartphone
• Conditions requiring greater than outpatient care

Where it is running

• Ohio State University — Columbus, Ohio, United States (enrolling)

Full record on ClinicalTrials.gov

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