Prospective Study of Antiplatelet and Anticoagulation Therapy in Hereditary Haemorrhagic Telangiectasia

Recruiting now · Not applicable

Conditions studied: Hereditary Hemorrhagic Telangiectasia, Rendu Osler Disease

In brief

The goal of this clinical trial is to evaluate in real life, in patients with Hereditary Hemorrhagic Telangiectasia (HHT), the tolerance of the strategy of use of anticoagulant and/or antiplatelet, by comparing a new exposure period (first trimester of treatment) to a period of reference non-exposure (last trimester before start of treatment).

Key facts

Study ID

NCT05641142

Run by

University Hospital, Clermont-Ferrand

People needed

100

Starts

2023-04-07

Expected to finish

2029-04-01

Last updated by the study team

2026-07-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient with Rendu-Osler disease with an indication of antiplatelet and/or anticoagulant introduced for less than 3 months (inclusion period within 3 months of exposure)
• Age > 18 years old
• Patient able to understand and agree to participate in the study
• Affiliation to a social security system

You may not qualify if…

• Patient with an indication of antiplatelet and/or anticoagulant but for whom treatment has not been introduced or introduced for more than 3 months
• Refusal to participate
• Pregnant woman or who are breast feeding
• Patients under maintenance of justice, wardship or legal guardianship

Where it is running

• CHU d'Angers — Angers, France (enrolling)
• CHU de Bordeaux — Bordeaux, France (enrolling)
• CHU de Nantes — Nantes, France (enrolling)
• CHU de Nice — Nice, France (enrolling)
• AP-HP - Hôpital Ténon — Paris, France (enrolling)
• CHU de Rennes — Rennes, France (enrolling)
• CHRU de Strasbourg — Strasbourg, France (enrolling)
• CHU de Caen Normandie — Caen, France (enrolling)
• CHU clermont-ferrand — Clermont-Ferrand, France (enrolling)
• CHU de Dijon — Dijon, France (enrolling)
• Hospices Civiles de Lyon — Lyon, France (enrolling)
• CHU de Montpellier — Montpellier, France (enrolling)
• CHU de Nancy — Nancy, France (enrolling)
• Hôpital Ambroise Paré — Boulogne-Billancourt, France
• CHU de Poitiers — Poitiers, France
• Assistance Publique - Hôpitaux de Marseille — Marseille, France
• CHU de Toulouse — Toulouse, France
• CHRU de Lille — Lille, France

Full record on ClinicalTrials.gov

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