Beyond Monoamines: The Role of the Nociceptin/Orphanin FQ Receptor in Major Depression
Recruiting now
Conditions studied: Major Depressive Disorder
In brief
This study looks at the role of the Nociceptin/Orphanin FQ receptor system in the brain of individuals with current or past major depressive disorder (MDD). It also examines how individuals with a history of depression make certain decisions and which brain regions are involved in such decisions. Information collected through MRI, PET, biospecimens (i.e., blood, saliva) and behavioral tasks will be used to predict depressive symptoms in the future.
Key facts
- Study ID
- NCT05630963
- Run by
- Mclean Hospital
- People needed
- 228
- Starts
- 2021-12-29
- Expected to finish
- 2027-02-28
- Last updated by the study team
- 2025-10-21
Who can join
Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.
Where it is running
- McLean Hospital — Belmont, Massachusetts, United States (enrolling)
Full record on ClinicalTrials.gov
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