A Study to Evaluate the Effects of Cenicriviroc Mesylate on Arterial Inflammation in People Living With HIV
Completed · Phase 2 · Has a placebo group
Conditions studied: HIV-1-infection, Elevated Cardiovascular Risk
In brief
The study was conducted to determine if cenicriviroc mesylate (CVC) would decrease vascular inflammation as measured by 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) imaging of the aorta and carotid arteries.
Key facts
- Study ID
- NCT05630885
- Run by
- National Institute of Allergy and Infectious Diseases (NIAID)
- People needed
- 110
- Starts
- 2023-05-30
- Expected to finish
- 2024-06-19
- Last updated by the study team
- 2025-07-16
Who can join
Age: 45 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of California, Los Angeles CARE Center CRS (Site # 601) — Los Angeles, California, United States
- UCSD Antiviral Research Center CRS (Site # 701) — San Diego, California, United States
- UCSF HIV/AIDS CRS (Site # 801) — San Francisco, California, United States
- Harbor University of California Los Angeles Center CRS (Site # 603) — Torrance, California, United States
- Northwestern University CRS (Site # 2701) — Chicago, Illinois, United States
- Massachusetts General Hospital CRS (MGH CRS) (Site # 101) — Boston, Massachusetts, United States
- Brigham and Women's Hospital Therapeutics (BWH TCRS) CRS (Site # 107) — Boston, Massachusetts, United States
- Washington University Therapeutics (WT) CRS (Site # 2101) — St Louis, Missouri, United States
- Weill Cornell Chelsea CRS (Site # 7804) — New York, New York, United States
- Weill Cornell Uptown CRS (Site # 7803) — New York, New York, United States
- University of Rochester Adult HIV Therapeutic Strategies Network CRS (Site # 31787) — Rochester, New York, United States
- Chapel Hill CRS (Site # 3201) — Chapel Hill, North Carolina, United States
- Cincinnati CRS (Site # 2401) — Cincinnati, Ohio, United States
- Case CRS (Site # 2501) — Cleveland, Ohio, United States
- Ohio State University CRS (Site # 2301) — Columbus, Ohio, United States
- University of Pittsburgh CRS (Site # 1001) — Pittsburgh, Pennsylvania, United States
- Vanderbilt Therapeutics (VT) CRS (Site # 3652) — Nashville, Tennessee, United States
- Houston AIDS Research Team CRS (Site # 31473) — Houston, Texas, United States
- University of Washington Positive Research CRS (Site # 1401) — Seattle, Washington, United States
Full record on ClinicalTrials.gov
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