A Combined Neurofeedback-TMS Intervention for Alcohol Use Disorder

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Alcohol Use Disorder

In brief

The goal of this clinical study is to test the effectiveness of a supplemental fMRI neurofeedback and/or TMS intervention in individuals seeking treatment for Alcohol Use Disorder. After an initial visit, participants will come in once a week for four (4) weeks for an intervention session, which may or may not include TMS and MRI. Participants will be contacted for monthly follow-ups (remotely) for up to 12 months and will be asked to come in for two MRI follow-ups at 6 and 12 months.

Key facts

Study ID: NCT05621538
Run by: Auburn University
People needed: 90
Starts: 2025-10-01
Expected to finish: 2026-03-31
Last updated by the study team: 2025-10-07

Who can join

Age: 19 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Age 19-65
Receiving treatment for Alcohol Use Disorder

You may not qualify if…

MRI Contraindications
Presence of metal in the body that would make having a 7T MRI unsafe (including facial tattoos)
Claustrophobia, such that individual would be unable to stay in the MRI for up to 1 hr
Hearing loss, including tinnitus, that might be made worse by MRI or TMS
TMS Contraindications
Has ever had a seizure, or has a family history of epilepsy
Taking medications or substances that lower the seizure threshold
Implanted devices that are in the head or rely on physiological signals
History of neurological disease, such as stroke or brain tumor
Head injury with loss of consciousness greater than 30 minutes
Actively withdrawing from alcohol
Family history of schizophrenia or presence of psychotic symptoms

Where it is running

Auburn University — Auburn, Alabama, United States (enrolling)

Full record on ClinicalTrials.gov

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